PUBLICATIONS

Vacante F, Rodor J, Lalwani MK, Mahmoud AD, Bennett M, De Pace AL, Miller E, van Kuijk K, de Bruijn JB, Gijbels M, Williams TC, Clark MB, Scanlon JP, Doran AC, Montgomery R, Newby DE, Giacca M, O’Carroll D, Hadoke PW, Denby L, Sluimer JC, and Baker AH. “CARMN Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice”. Circ Res. 2021; PMID: 33622045

Tao W, Turdagul A Jr, Kong N, Li W, Wang X, Doran AC, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, and Shi J. “siRNA nanoparticles targeting CaMKIIy in lesional macrophages improve atherosclerotic plaque stability in mice”. Sci Transl Med 2020; 12(553):eaay1063. PMID: 32718990

Doran AC, Yurdagul A Jr, and Tabas I. “Efferocytosis in Health and Disease”. Nat Rev Immunology 2020; 20(4):254-267. PMID: 31822793.

Liu T, Xiang A, Peng T, Doran AC, Tracey KJ, Barnes BJ, Tabas I, Son M, and Diamond B. “HMGB1-C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediators biosynthesis.” Proc Natl Acad Sci USA 2019; 116(46):23254-23263. PMID: 31570601.

Linton MF, Yancey PG, Davies SS, Jerome WG, Linton EF, Song WL, Doran AC, and Vickers KC. “The Role of Lipids and Lipoproteins in Atherosclerosis”. In: Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.: 2000-; 2019. PMID: 26844337.

Thomas DG, Doran AC, Fotakis P, Westerterp M, Antonson P, Jiang H, Jiang XC, Gustaffsson JA, Tabas I, Tall AR. “LXR suppresses inflammatory gene expression and neutrophil migration through cis-repression and cholesterol efflux”. Cell Reports 2018; 25(13):3774-3785. PMID: 30590048.

Moore KJ*^, Koplev S*, Fisher EA, Tabas I, Bjorkegren JLM*^, Doran AC*^ and Kovacic JC^. “Macrophage trafficking, inflammatory resolution, and genomics in atherosclerosis: JACC macrophage in CVD series (Part 2)”. Journal of the American College of Cardiology 2018; 72(18):2181-2197. PMID: 30360827.
*Denotes co-first authorship
^Denotes co-corresponding authorship

Proto JP*, Doran AC*, Gusarova G, Sozen E, Subramanian M, Islam MN, Rymond CC, Du J, Hook J, Kuriakose G, Bhattacharya J and Tabas I. “Regulatory T cells promote macrophage efferocytosis during inflammation resolution”. Immunity 2018; 49(4):666-677. PMID: 30291029.
*Denotes co-first authorship
Selected by Faculty of 1000

Cai B, Kasikara C, Doran AC, Ramakrishnan R, Birge RB and Tabas I. “MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity”. Science Signaling 2018; 11(549). PMID: 30254055.
Selected by Faculty of 1000

Kasikara, C, Doran AC^, Cai B and Tabas I^. “The role of non-resolving inflammation in atherosclerosis”. Journal of Clinical Investigation 2018; 128(7):2713-2723. PMID: 30108191.
^Denotes co-corresponding authorship

Proto JP, Doran AC, Subramanian M, Wang H, Zhang M, Sozen E, Rymond CC, Kuriakose G, Winchester R, Sykes M, Yang YG and Tabas I. “Hypercholesterolemia induces T cell expansion in humanized immune mice”. Journal of Clinical Investigation 2018; 128(6):2370-2375. PMID: 29708512.
Selected by Faculty of 1000

Yurdagul A, Doran AC, Cai B, Fredman G and Tabas I. “Mechanisms and consequences of defective efferocytosis in atherosclerosis”. Frontiers in Cardiovascular Medicine 2018; 4(86): 1-10. PMID: 29379788.

Doran AC, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond CC, Dorweiler B, Sluimer J, Hsieh J, Kuriakose G, Tall AR and Tabas I. “CaMKIIg suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis”. Journal of Clinical Investigation 2017; 127(11):4075-4089. PMID: 28972541.

Cai B, Thorp EB, Doran AC, Sansbury BE, Spite M, Fredman G, Wang Y, Daemen MJAP, Dorweiler B and Tabas I. “MerTK Cleavage Promotes Plaque Necrosis and Defective Resolution in Atherosclerosis”. Journal of Clinical Investigation 2017; 127(2):564-568. PMID: 28067670

Cai B, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G and Tabas I. “MerTK Cleavage Limits Pro-Resolving Mediator Biosynthesis and Exacerbates Tissue Inflammation”. Proceedings of the National Academy of Sciences 2016; 113(23): 6526-31. PMID: 27199481

Colombo PC, Doran AC, Onat D, Wong KY, Ahmad M, Sabbah HN and Demmer RT. “Venous Congestion, Endothelial and Neurohormonal Activation in Acute Decompensated Heart Failure”. Current Heart Failure Reports 2015; 12(3):215-22. PMID: 25740404

Lipinski MJ, Campbell KA, Duong SQ, Welch J, Garmey JC, Doran AC, Skaflen MD, Oldham SN, Kelly KA, McNamara CA. “Loss of Id3 increases VCAM-1 expression, macrophage accumulation and atherogenesis in Ldlr-/- mice”. Arteriosclerosis, Thrombosis and Vascular Biology 2012; 32(12):2855-61. PMID: 23042815

Campbell KA, Lipinski MJ, Doran AC, Skaflen MD, Fuster V and McNamara CA. “Lymphocytes and the Adventitial Response to Atherosclerosis”. Circulation Research 2012; 110(6):889-900. PMID: 22427326

Cutchins A, Harmon DB, Kirby J, Doran AC, Oldham SN, Skaflen MD, Meller N, Keller SR and McNamara CA. “Inhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansion and insulin sensitivity”. Arteriosclerosis, Thrombosis and Vascular Biology 2012; 32(2):317-24. PMID: 22075252

Doran AC, Lipinski MJ, Oldham SN, Garmey JC, Skaflen MD, Cutchins A, Lee DJ, Glover DK, Kelly KA, Galkina EV, Ley K, Tsimikas S, Bender TP and McNamara CA. “B-cell aortic homing and atheroprotection depend on Id3”. Circulation Research 2012; 110(1):e1-12. PMID: 22034493

Bagavant H, Scindia Y, Nackeiwicz D, Nandula SR, Doran AC, Cutchins A, Oldham S, Deshmukh U and McNamara C. “Deficiency of a transcriptional regulator, Inhibitor of differentiation 3, induces glomerulonephritis in Apolipoprotein E-deficient mice: a model linking hyperlipidemia and renal disease”. American Journal of Pathology 2011; 179(2):651-60. PMID: 21801865

Lipinski MJ, Perry HM, Doran AC, Oldham SN and McNamara CA. “Comment on ‘Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis’”. Journal of Immunology 2011; 186(1):4. PMID: 21172871

Deliri H, Meller N, Kadakkal A, Malhotra R, Brewster J, Doran AC, Pei H, Oldham SN, Skaflen MD, Garmey JC and McNamara CA. “Increased 12/15-lipoxygenase enhances cell growth, fibronectin deposition and neointimal formation in response to carotid injury”. Arteriosclerosis, Thrombosis and Vascular Biology. 2011; 31(1):110-116. PMID: 20947825

Doran AC, Lehtinen AB, Meller N, Lipinski MJ, Slayton RP, Oldham SN, Skaflen MD, Yeboah J, Rich SS, Bowden DW and McNamara CA. “Id3 is a novel atheroprotective factor containing a functionally significant SNP associated with intima-media thickness in humans”. Circulation Research 2010; 106(7):1303-1311. PMID: 20185798

Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, Johnstone SR, Elliott MR, Gruber F, Han J, Chen W, Kensler T, Ravichandran KS, Isakson BE, Wamhoff BR and Leitinger N. “Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf-2”. Circulation Research 2010; 107(6):737-746. PMID: 20651288

Doran AC, Meller N, Cutchins A, Deliri H, Slayton RP, Oldham SN, Kim JB, Keller SR and McNamara CA. “The helix-loop-helix factors Id3 and E47 are novel regulators of adiponectin”. Circulation Research 2008; 103(6):624-634. PMID: 18669923 (With accompanying editorial by Rahmouni, et al)

Doran AC, Meller N and McNamara CA. “The role of smooth muscle cells in the initiation and early progression of atherosclerosis”. Arteriosclerosis, Thrombosis and Vascular Biology 2008; 28(5):812-819. PMID: 18276911

Doran AC, Wan YP, Kopin AS and Beinborn M. “Established theory of radiation-induced decay is not generalizable to Bolton-Hunter labeled peptides”. Biochemical Pharmacology 2003; 65(9):1515-1520. PMID: 12732364